Systemic Distribution of Talc
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چکیده
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منابع مشابه
Systemic distribution of talc after intrapleural administration in rats.
STUDY OBJECTIVES Many reports have shown the efficacy of talc to induce an effective pleurodesis. However, there is little information about the side effects related to this sclerosing agent. The objective of this experimental study is to recognize the systemic distribution of talc after its instillation into the pleural space of rats. DESIGN Forty animals were assigned to receive talc throug...
متن کاملInflammation and clinical repercussions of pleurodesis induced by intrapleural talc administration.
Although reports on pleurodesis date back to the beginning of the 20th century, the search for the ideal sclerosing agent is ongoing. Several agents have been studied and used, but talc continues to be the most popular. However, potentially harmful systemic side effects have been associated with talc pleurodesis. In this article we discuss the likely mechanisms of pleural inflammation and pleur...
متن کاملRefractory massive pleural effusion in systemic lupus erythematosus treated with talc poudrage.
The case of a 31-year-old black male is presented with recurrent pleural effusion secondary to active SLE. Treatment with corticosteroids, azathioprine, plaquenil, and tetracycline pleural sclerosis was unsuccessful. Disease control was finally achieved by pleural talc poudrage.
متن کاملSmall particle-size talc is associated with poor outcome and increased inflammation in thoracoscopic pleurodesis.
RATIONALE Talc is very effective for pleurodesis, but there is concern about complications, especially acute respiratory distress syndrome. OBJECTIVES It was the aim of this study to investigate if talc with a high concentration of small particles induces greater production of cytokines, and if pleural tumor burden has any influence on the local production and spillover of cytokines to the sy...
متن کاملInfluence of particle size on extrapleural talc dissemination after talc slurry pleurodesis.
BACKGROUND Cases of acute respiratory failure reported after talc pleurodesis have raised concerns about its safety. It has been speculated that this pulmonary inflammatory syndrome is secondary to the extrapleural dissemination of the talc particles. STUDY OBJECTIVES To test the hypothesis that particle size influences extrapleural talc deposition and pleural inflammation after talc slurry p...
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تاریخ انتشار 1999